Dietary bovine beta-lactoglobulin is transferred to human milk

Acta Paediatr Scand. 1985 May;74(3):342-5. doi: 10.1111/j.1651-2227.1985.tb10981.x.


Human milk from 38 mothers was analysed by radioimmunological method for content of bovine beta-lactoglobulin. Detectable amounts (5-33 micrograms/l) of immunoactive beta-lactoglobulin were found in 18 human milk samples. Milk from 3 mothers, whose infants suffered from infantile colic contained high amounts of beta-lactoglobulin (32, 18 and 14 micrograms/l respectively). With the mothers on a cow's milk free diet the contents fell to non-detectable amounts in two mothers and to 6 micrograms/l in the third. All three infants became free from colic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle
  • Colic / etiology*
  • Female
  • Humans
  • Infant, Newborn
  • Lactoglobulins / analysis*
  • Milk / adverse effects
  • Milk, Human / analysis*
  • Radioimmunoassay


  • Lactoglobulins