Osteoma cutis

BMJ Case Rep. 2025 Mar 3;18(3):e262591. doi: 10.1136/bcr-2024-262591.

Abstract

In this report, we discuss two children with progressive cutaneous ossification and review its aetiology and associations. Osteoma cutis (OC) is a cutaneous disease associated with ossification in the dermis or subcutaneous tissue, classified as either primary or secondary. Primary OC is rare. Although it can occur de novo, it has significant genetic and metabolic associations that must be excluded and warrants a thorough clinical workup. Secondary OC arises in response to inflammation, neoplasia or trauma and may have aesthetic concerns.

Keywords: Dermatology; Genetics; Pediatrics.

Publication types

  • Case Reports

MeSH terms

  • Bone Diseases, Metabolic* / diagnosis
  • Bone Diseases, Metabolic* / pathology
  • Child
  • Diagnosis, Differential
  • Humans
  • Ossification, Heterotopic* / diagnosis
  • Ossification, Heterotopic* / etiology
  • Ossification, Heterotopic* / pathology
  • Skin Diseases, Genetic* / diagnosis
  • Skin Diseases, Genetic* / pathology

Supplementary concepts

  • Osseous Heteroplasia, Progressive