Mesangial IgA deposits with steroid responsive nephrotic syndrome: probable minimal lesion nephrosis

Am J Kidney Dis. 1985 May;5(5):267-9. doi: 10.1016/s0272-6386(85)80120-7.

Abstract

Two children presented with nephrotic syndrome. Renal biopsy demonstrated minimal lesion nephrosis with mesangial IgA deposits. Response to prednisone therapy was prompt in both cases. The clinical and histologic features of these and other reported cases suggested a diagnosis of minimal lesion nephrosis and not IgA nephropathy (Berger's disease).

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Glomerular Mesangium / immunology*
  • Glomerular Mesangium / pathology
  • Glomerulonephritis, IGA / complications
  • Glomerulonephritis, IGA / diagnosis*
  • Humans
  • Immunoglobulin A / analysis*
  • Male
  • Nephrosis, Lipoid / diagnosis
  • Nephrotic Syndrome / complications
  • Nephrotic Syndrome / diagnosis*
  • Nephrotic Syndrome / drug therapy
  • Prednisone / therapeutic use

Substances

  • Immunoglobulin A
  • Prednisone