Tuberculosis-Preventive Treatment for Household Contacts at Health Facility and Community Settings in Pakistan

Clin Infect Dis. 2025 Jul 18;80(6):1290-1292. doi: 10.1093/cid/ciaf088.

Abstract

We assessed incremental completion of tuberculosis-preventive treatment cascade in household contacts by offering services in community settings. This improved clinical evaluation by 12.4 (95% CI: 11.7-13.0) percentage points (pp), treatment completion by 11.6 (95% CI: 10.6-12.7) pp, and cascade completion by 5.9 (95% CI: 5.1-6.7) pp.

Keywords: TB infection; TB preventive treatment; completion; shorter regimen; uptake.

MeSH terms

  • Adolescent
  • Adult
  • Antitubercular Agents* / administration & dosage
  • Antitubercular Agents* / therapeutic use
  • Child
  • Child, Preschool
  • Contact Tracing
  • Family Characteristics
  • Female
  • Health Facilities
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Pakistan / epidemiology
  • Tuberculosis* / drug therapy
  • Tuberculosis* / epidemiology
  • Tuberculosis* / prevention & control
  • Young Adult

Substances

  • Antitubercular Agents

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