Monochorionic Twin Gestation

Clin Obstet Gynecol. 2025 Sep 1;68(3):366-382. doi: 10.1097/GRF.0000000000000927. Epub 2025 Mar 5.

Abstract

Care of the pregnant patient with monochorionic (MC) twin gestation entails specific steps that are imperative in recognizing complications that are unique to MC placentation. Here, we will review recommendations for care of the patient with known MC twin gestation, as well as discuss the pathophysiology, diagnosis, and management of these complications including, but not limited to, twin-twin transfusion syndrome (TTTS), twin anemia-polycythemia sequence (TAPS), selective fetal growth restriction (SFGR), and twin reversed arterial perfusion (TRAP) sequence.

Keywords: SFGR; TAPS; TRAP sequence; TTTS; monochorionic twins; selective fetal growth restriction; twin anemia-polycythemia sequence; twin-twin transfusion syndrome.

Publication types

  • Review

MeSH terms

  • Anemia / diagnosis
  • Anemia / therapy
  • Female
  • Fetal Growth Retardation / diagnosis
  • Fetal Growth Retardation / therapy
  • Fetofetal Transfusion* / diagnosis
  • Fetofetal Transfusion* / physiopathology
  • Fetofetal Transfusion* / therapy
  • Humans
  • Polycythemia / diagnosis
  • Polycythemia / therapy
  • Pregnancy
  • Pregnancy, Twin*
  • Twins, Monozygotic*
  • Ultrasonography, Prenatal