Fast face-selective responses in prefrontal face patches of the macaque

Abstract

Face processing models propose gradually more complex receptive field properties culminating in invariant representations in anterior inferotemporal cortex (aITC), leading to late socio-emotionally relevant encoding in pre- and orbitofrontal cortex (POC). Top-down facilitation models, however, predict that some lower-level POC neurons respond faster than aITC. To resolve this discrepancy, we recorded from 2,459 neurons in fMRI-defined POC and aITC face patches. POC patches are more heterogeneous, containing smaller fractions of face-selective neurons than aITC and a mixture of responses to faces and non-faces. In one POC patch, face responses are surprisingly fast, outpacing those in aITC. Moreover, its responses correlate inversely with stimulus spatial frequency. Hence, our extensive data, with a large diversity of POC neurons, support both models and suggest one POC face patch might be specialized in fast, low-level face processing, which may enable (partially) invariant face representations during subsequent processing stages in inferotemporal cortex (ITC).

Keywords: CP: Neuroscience; category selectivity; fMRI; face processing; inferotemporal cortex; orbitofrontal cortex; prefrontal cortex; receptive field; response latency; rhesus monkey; single-unit recordings.