The incidence and severity of post-asphyxial encephalopathy in full-term infants

Early Hum Dev. 1985 May;11(1):21-6. doi: 10.1016/0378-3782(85)90115-x.


The incidence of clinically significant birth asphyxia was assessed over a 4-year period in a busy teaching hospital maternity hospital. The overall incidence was 6.0 per 1000 live-born deliveries of whom 2.1 per 1000 showed severely abnormal features including seizures or coma. There was a marked seasonal distribution (more common in winter than summer months) and intrauterine growth retardation occurred in 25% of asphyxiated infants. Only 1.6% of these infants were large for gestation age. There is some evidence that the incidence of this condition has not changed over a 10-year period.

MeSH terms

  • Apgar Score
  • Asphyxia Neonatorum / complications*
  • Birth Weight
  • Brain Diseases / epidemiology
  • Brain Diseases / etiology*
  • Brain Diseases / physiopathology
  • Humans
  • Infant, Newborn