Thermal denaturation of donor cornea: an unusual complication of penetrating keratoplasty

Ophthalmic Surg. 1978 Oct;9(5):47-51.


A most unusual complication of penetrating keratoplasty is the rapid thermal denaturation of a human donor cornea upon accidental exposure to temperature of 50 degrees to 60 degrees C, the result of inadequate cooling of a Teflon trephine block following autoclave sterilization.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cornea / pathology
  • Cornea / ultrastructure
  • Corneal Transplantation*
  • Hot Temperature / adverse effects*
  • Humans
  • Male
  • Sterilization / methods
  • Transplantation, Homologous / instrumentation