Toxic psychosis: a complication of antimalarial therapy

J Am Acad Dermatol. 1985 May;12(5 Pt 1):863-5. doi: 10.1016/s0190-9622(85)70109-0.


A case is reported of toxic psychosis in a patient with a diagnosis of discoid lupus erythematosus treated with hydroxychloroquine. The dose slightly exceeded the maximum recommended dose for 10 days because of a pharmacy error. Since more antimalarials are being used for various diseases, attention is called to this possible complication with a subtle onset.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Humans
  • Hydroxychloroquine / administration & dosage
  • Hydroxychloroquine / adverse effects*
  • Hydroxychloroquine / therapeutic use
  • Lupus Erythematosus, Discoid / drug therapy
  • Male
  • Medication Errors
  • Psychoses, Substance-Induced / etiology*


  • Hydroxychloroquine