Summary of best evidence on self-management in adult patients with systemic lupus erythematosus

Lupus. 2025 Apr;34(5):439-451. doi: 10.1177/09612033251325687. Epub 2025 Mar 17.

Abstract

ObjectiveTo evaluate and summarize the best evidence on self-management in adult patients with systemic lupus erythematosus (SLE) and provide evidence-based recommendations in clinical settings.MethodsLiteratures related to self-management of SLE patients were searched in the guideline websites, professional association websites and relevant databases, including clinical decisions, guidelines, expert consensus, best practice recommendations, evidence summaries, meta-analyses, systematic reviews and randomized controlled trials, etc. The search time was from January 2018 to September 2023.ResultsA total of 19 literatures were included, consisting of 9 guidelines, 4 expert consensus, 4 clinical decisions, and 2 systematic reviews, and 49 pieces of evidence were extracted. After sorting and discussing, the evidence were integrated into six aspects: skin management, diet management, exercise management, vaccination management, complication management, as well as follow-up and lifestyle management.ConclusionThe best evidence of self-management in SLE patients summarized in this study is of high quality, which can provide evidence-based recommendations for clinical medical staff and patients, so as to help self-management of SLE patients in a more scientific and effective way.

Keywords: Systemic lupus erythematosus; evidence-based nursing; self-management.

MeSH terms

  • Adult
  • Evidence-Based Medicine
  • Humans
  • Lupus Erythematosus, Systemic* / therapy
  • Practice Guidelines as Topic
  • Self-Management* / methods