Structure and genomic organization of a new family of murine retrovirus-related DNA sequences (MuRRS)

Nucleic Acids Res. 1985 May 24;13(10):3461-70. doi: 10.1093/nar/13.10.3461.

Abstract

A new class of murine retrovirus-related sequences (MuRRS) is described. These 5.7 kb long transposon-like DNA-elements start and end with approximately 600 bp long repeats identical to previously identified solitary LTR-like elements (LTR-IS). There are about 50 - 100 5.7 kb elements and about 500 - 1000 solo LTR-IS elements per mouse haploid genome. Sequence analysis of one cloned MuRRS element revealed several possible open reading frames with partial sequence homologies to retroviral gag, pol and env genes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • DNA, Viral / analysis*
  • Genes, Viral*
  • Mice
  • Nucleic Acid Hybridization
  • Recombination, Genetic
  • Repetitive Sequences, Nucleic Acid
  • Retroviridae / genetics*

Substances

  • DNA, Viral

Associated data

  • GENBANK/X02487