Cardiac impantable electronic device infective endocarditis (CIED-IE) is a life-threatening condition. We report 2 cases of large infective endocarditis in which differences in surgical timing affected outcomes. Patients with CIED-IE should be referred to a hub center with experienced specialists and undergo early complete device extraction without unnecessary delay.
Keywords: cardiac implantable electronic device; endocarditis; management.
Copyright © 2025 The Authors. Published by Elsevier Inc. All rights reserved.