Embolic stroke complicating left ventricular thrombus in Takotsubo syndrome: A case report

J Int Med Res. 2025 Mar;53(3):3000605251326764. doi: 10.1177/03000605251326764. Epub 2025 Mar 22.

Abstract

This study investigated the occurrence of left ventricular thrombus formation and subsequent embolic stroke in patients with Takotsubo syndrome. Through the case analysis of an 80-year-old Chinese elderly female patient, it was found that although Takotsubo syndrome is generally considered a self-limiting disease, it can lead to severe complications such as left ventricular thrombus and cerebral stroke. The patient experienced a cardioembolic stroke during hospitalization, and magnetic resonance imaging revealed acute cerebral vascular occlusion. This case highlights the importance of anticoagulation therapy, especially in the prevention of thromboembolic events in patients with Takotsubo syndrome complicated with intracardiac thrombosis.

Keywords: Takotsubo syndrome; anticoagulation; cardioembolic strokes; magnetic resonance imaging; ventricular thrombus.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anticoagulants / therapeutic use
  • Echocardiography
  • Embolic Stroke* / complications
  • Embolic Stroke* / etiology
  • Female
  • Heart Diseases / complications
  • Heart Diseases / diagnosis
  • Heart Diseases / diagnostic imaging
  • Heart Diseases / etiology
  • Heart Ventricles* / diagnostic imaging
  • Heart Ventricles* / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Takotsubo Cardiomyopathy* / complications
  • Takotsubo Cardiomyopathy* / diagnostic imaging
  • Thrombosis* / complications
  • Thrombosis* / diagnostic imaging

Substances

  • Anticoagulants