"De novo" aneurysms. A clinical review

Surg Neurol. 1985 Aug;24(2):173-80. doi: 10.1016/0090-3019(85)90181-8.


The authors present seven cases drawn from 620 consecutive cases over 30 years, in which previously undemonstrated (hence "de novo") intracranial aneurysms formed and ruptured at intervals of 3-20 years, after clipping of an initial aneurysm. Six patients were treated for rupture of a second aneurysm. All six had undergone successful treatment of a previous aneurysm; pre- and postoperative angiography showed not only successful clipping of the first aneurysm but also no incidence of multiple aneurysms. In no case was a major artery occluded at the time of the initial surgery. The implications as to natural history and the advisability of repeated arteriography in some patients with aneurysms are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cerebral Angiography
  • Female
  • Humans
  • Intracranial Aneurysm / diagnostic imaging
  • Intracranial Aneurysm / epidemiology*
  • Intracranial Aneurysm / etiology
  • Intracranial Aneurysm / surgery
  • Male
  • Middle Aged
  • Postoperative Period
  • Subarachnoid Hemorrhage / complications
  • Time Factors