Metabolic and Bariatric Surgery Utilization in the Era of Glucagon-Like Peptide-1 Receptor Agonists among Adolescents versus Adults

Sarah E Messiah; Deepali K Ernest; Folefac D Atem; Faisal G Qureshi; M Sunil Mathew; Jackson M Francis; Alicia Wheelington; Marlyn A Allicock; Bethany R Cartwright; Benjamin E Schneider; Nestor de la Cruz-Muñoz; Steven E Lipshultz; Ildiko Lingvay; Jaime P Almandoz; Sarah E Barlow

doi:10.1016/j.jpeds.2025.114564

Metabolic and Bariatric Surgery Utilization in the Era of Glucagon-Like Peptide-1 Receptor Agonists among Adolescents versus Adults

J Pediatr. 2025 Jul:282:114564. doi: 10.1016/j.jpeds.2025.114564. Epub 2025 Mar 23.

Authors

Affiliations

¹ Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX; Children's Health System of Texas, Children's and UTSW, Dallas, TX. Electronic address: Sarah.Messiah@UTSouthwestern.edu.
² University of Texas Health Science Center at Houston, School of Public Health, Houston, TX.
³ Children's Health System of Texas, Children's and UTSW, Dallas, TX; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX.
⁴ Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX; Children's Health System of Texas, Children's and UTSW, Dallas, TX.
⁵ Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX.
⁶ Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX; Children's Health System of Texas, Children's and UTSW, Dallas, TX; Touchstone Diabetes Center, University of Texas Southwestern Medical Center, Dallas, TX.
⁷ Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX.
⁸ Dewitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL.
⁹ Department of Pediatrics, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY.
¹⁰ Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX; Division of Endocrinology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
¹¹ Division of Endocrinology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
¹² Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX; Children's Health System of Texas, Children's and UTSW, Dallas, TX.

Abstract

This cross-sectional study analyzed adolescent metabolic and bariatric surgery (MBS) utilization before and after glucagon-like peptide-1 receptor agonist (GLP-1RA) medication approval, comparing trends across race and ethnic groups. Although both MBS and GLP-1RA are effective weight management strategies, adolescent MBS utilization increased, while adult rates declined from 2021 through 2023.

Keywords: adolescents; adults; bariatric surgery; prevalence.

Publication types

Comparative Study

MeSH terms

Adolescent
Adult
Bariatric Surgery* / statistics & numerical data
Bariatric Surgery* / trends
Cross-Sectional Studies
Diabetes Mellitus, Type 2* / drug therapy
Female
Glucagon-Like Peptide-1 Receptor Agonists*
Humans
Male
Young Adult

Substances

Glucagon-Like Peptide-1 Receptor Agonists

Abstract

Publication types

MeSH terms

Substances

Grants and funding