Effects of aquatic high-intensity interval training on aerobic capacity in adults with rheumatic and musculoskeletal diseases: the AquaHigh randomised controlled trial

BMJ Open. 2025 Mar 24;15(3):e090612. doi: 10.1136/bmjopen-2024-090612.

Abstract

Objectives: To examine the effects of 12 weeks aquatic high-intensity interval training (AHIIT) compared with aquatic moderate-intensity continuous training (AMICT) on aerobic capacity and lower limb functional strength in adults with rheumatic and musculoskeletal diseases (RMDs).

Design: An assessor-blinded randomised controlled trial.

Setting: Community-based setting.

Participants: 89 participants (91% female, mean age 62 (SD 13) years) with RMDs were randomly allocated to AHIIT (n=44) or AMICT (n=45).

Interventions: Both groups participated in group-based peer-led exercise programmes two times per week for 12 weeks. The AHIIT group included four intervals of 4 min at high intensity (Borg scale 14-18). The AMICT group maintained moderate continuous intensity level (Borg scale 12-13).

Main outcome measures: Peak aerobic capacity (VO2peak) was estimated by time to exhaustion and lower limb functional strength with the 30-second sit-to-stand test (30sSTS) at baseline, 3 months and 6 months. A linear mixed model for repeated measures estimated the mean difference with 95% CI in VO2peak and 30sSTS.

Results: Mean exercise intensity was Borg scale 15 (SD 2) and 13 (SD 2) in the AHIIT and AMICT, respectively. Mean improvement in VO2peak in AHIIT was 1.9 mL∙kg-1∙min-1 (95% CI 0.045 to 3.77) compared with AMICT after 12 weeks (p<0.05). There was no statistically significant difference between groups in VO2peak after 6 months or in 30sSTS at either 3 or 6 months (p>0.05). No adverse events during exercise were reported.

Conclusions: AHIIT demonstrated significant improvements in aerobic capacity after 12 weeks, and the intervention was well tolerated with no adverse events reported. However, there was no maintenance of aerobic capacity at 6 months.

Trial registration number: NCT05209802.

Keywords: Exercise; REHABILITATION MEDICINE; RHEUMATOLOGY.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Exercise Therapy* / methods
  • Exercise Tolerance* / physiology
  • Female
  • High-Intensity Interval Training* / methods
  • Humans
  • Lower Extremity
  • Male
  • Middle Aged
  • Muscle Strength / physiology
  • Musculoskeletal Diseases* / physiopathology
  • Musculoskeletal Diseases* / rehabilitation
  • Musculoskeletal Diseases* / therapy
  • Oxygen Consumption
  • Rheumatic Diseases* / physiopathology
  • Rheumatic Diseases* / rehabilitation
  • Rheumatic Diseases* / therapy
  • Single-Blind Method

Associated data

  • ClinicalTrials.gov/NCT05209802