Central nervous system involvement in patients with acquired immune deficiency syndrome (AIDS)

Acta Neurol Scand. 1985 May;71(5):337-53. doi: 10.1111/j.1600-0404.1985.tb03211.x.


Central nervous system involvement occurred in 28 of 121 patients with acquired immune deficiency syndrome (AIDS). The major risk factor in this AIDS population was intravenous drug abuse (64%). A neurologic symptom or disability was the principal reason for hospitalization in 16 cases (57%). Three patients had primary lymphoma of the brain and the remainder had opportunistic infections. Patients with focal neurological features usually had toxoplasmosis. Progressive headache and meningeal signs occurred with cryptococcosis. A progressive subacute dementia was probably due to cytomegalovirus. Other infections included atypical mycobacteria, candida, herpes zoster and possible progressive multifocal leukoencephalopathy.

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Brain Abscess / complications
  • Brain Abscess / diagnostic imaging
  • Brain Diseases / complications
  • Central Nervous System Diseases / complications*
  • Female
  • Humans
  • Lymphoma / complications
  • Male
  • Mycobacterium Infections / complications
  • Mycoses / complications
  • Tomography, X-Ray Computed
  • Toxoplasmosis / complications
  • Virus Diseases / complications