Linear regressions in the calculation of lethal gene equivalents in man

Ann Hum Biol. May-Jun 1985;12(3):287-9. doi: 10.1080/03014468500007791.

Abstract

Linear regressions have been used extensively for the calculation of lethal gene equivalents in human populations. There are considerable theoretical and practical objections to the use of the method for this purpose.

MeSH terms

  • Consanguinity*
  • Genes, Lethal*
  • Genetics, Population*
  • Humans
  • Models, Genetic
  • Regression Analysis*