Evaluation of Serum Vitamin D and C Concentrations in Cats With Gingivostomatitis

Vet Med Sci. 2025 May;11(3):e70279. doi: 10.1002/vms3.70279.

Abstract

Aim of study: To investigate serum vitamin C and D concentrations of cats suffering from gingivostomatitis.

Materials and methods: Serum concentrations of vitamins C and D were evaluated in 30 cats of various breeds, including 15 healthy cats and 15 with gingivostomatitis.

Results: Serum vitamin D concentration in the healthy cats (35.36 ± 15.39 ng/mL) was significantly higher than that of the cats with gingivostomatitis (17.54 ± 10.50 ng/mL) (p < 0.05). There was no difference in serum vitamin C concentration between the healthy cats (3.7 ± 0.74 mg/100 mL) and those with gingivostomatitis (3.1 ± 0.72 mg/100 mL) (p < 0.05).

Conclusion: The results of this study suggest that cats with gingivostomatitis are predisposed to vitamin D deficiency. Further studies are required to confirm this finding in a larger study sample and to investigate the potential utility of vitamin D supplementation.

Keywords: ascorbic acid | calcidiol | cat | caudal stomatitis | feline gingivitis | gingivostomatitis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Ascorbic Acid* / blood
  • Cat Diseases* / blood
  • Cats
  • Female
  • Gingivitis* / blood
  • Gingivitis* / veterinary
  • Male
  • Stomatitis* / blood
  • Stomatitis* / veterinary
  • Vitamin D Deficiency / veterinary
  • Vitamin D* / blood

Substances

  • Vitamin D
  • Ascorbic Acid