Chemical and biological properties of a cationic Tc-tetraamine complex

Int J Appl Radiat Isot. 1985 Apr;36(4):315-7. doi: 10.1016/0020-708x(85)90093-6.


The complex of 99Tc with the ligand 1,4,8,11-tetraazaundecane (2,3,2-tet) was prepared and was compared with the similar 99Tc complexes with ethylenediamine and 1,4,8,11-tetraazacyclotetradecane. The results are all consistent with the formula [TcO2(2,3,2-tet)]+. The biological behavior was tested with 99mTc in Wistar rats. A fast clearance via the kidneys was found, and no accumulation in any other organ was observed.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Ethylenediamines
  • Female
  • Heterocyclic Compounds
  • Heterocyclic Compounds, 1-Ring*
  • Isotope Labeling / methods
  • Organotechnetium Compounds*
  • Polyamines*
  • Rats
  • Rats, Inbred Strains
  • Technetium*
  • Tissue Distribution


  • Ethylenediamines
  • Heterocyclic Compounds
  • Heterocyclic Compounds, 1-Ring
  • Organotechnetium Compounds
  • Polyamines
  • technetium Tc 99m 1,4,8,11-tetraazaundecane
  • technetium Tc 99m cyclam
  • technetium Tc 99m ethylenediamine
  • Technetium