Cognitive disengagement syndrome symptoms in obsessive-compulsive disorder with and without attention deficit hyperactivity disorder

Nord J Psychiatry. 2025 May;79(4):264-271. doi: 10.1080/08039488.2025.2488386. Epub 2025 Apr 7.

Abstract

Objective: Comorbidity between Obsessive-Compulsive Disorder (OCD) and Attention Deficit/Hyperactivity Disorder (ADHD) appears complex in terms of etiology, phenomenology, and treatment. There is a need to identify possible factors which are related to the co-occurrence of OCD and ADHD in adults. Cognitive Disengagement Syndrome (CDS) may contribute to this comorbidity through its associations with ADHD, emotional dysregulation, cognitive processes, and neuropsychological deficits.

Methods: In this study, we compared CDS and various sociodemographic and clinical characteristics in OCD patients with (n = 44) and without ADHD (n = 72), and healthy controls (n = 43), using the Yale Brown Obsessive-Compulsive Scale, Wender Utah Rating Scale, Adult ADD/ADHD DSM-IV Based Diagnostic Screening and Rating Scale, Barkley's Adult Sluggish Cognitive Tempo Rating Scale, Beck Depression Inventory, and Beck Anxiety Inventory.

Results: In addition to contamination obsessions (OR = 7.733, p = 0.002), male gender (OR = 3.732, p = 0.031), high anxiety (OR = 1.053, p = 0.02), and high CDS symptoms (OR = 1.145, p = 0.037) were associated with comorbidity between OCD and ADHD.

Conclusion: We suggest that CDS may serve as a valuable construct for understanding the nature of comorbidity between OCD and ADHD.

Keywords: Obsessive-compulsive disorder; anxiety; attention deficit hyperactivity disorder cognitive disengagement syndrome; comorbidity; depression.

MeSH terms

  • Adult
  • Attention Deficit Disorder with Hyperactivity* / complications
  • Attention Deficit Disorder with Hyperactivity* / diagnosis
  • Attention Deficit Disorder with Hyperactivity* / epidemiology
  • Attention Deficit Disorder with Hyperactivity* / psychology
  • Comorbidity
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obsessive-Compulsive Disorder* / diagnosis
  • Obsessive-Compulsive Disorder* / epidemiology
  • Obsessive-Compulsive Disorder* / psychology
  • Syndrome
  • Young Adult