Aridicins, novel glycopeptide antibiotics. I. Taxonomy, production and biological activity

M C Shearer; P Actor; B A Bowie; S F Grappel; C H Nash; D J Newman; Y K Oh; C H Pan; L J Nisbet

doi:10.7164/antibiotics.38.555

Aridicins, novel glycopeptide antibiotics. I. Taxonomy, production and biological activity

J Antibiot (Tokyo). 1985 May;38(5):555-60. doi: 10.7164/antibiotics.38.555.

Authors

M C Shearer, P Actor, B A Bowie, S F Grappel, C H Nash, D J Newman, Y K Oh, C H Pan, L J Nisbet

PMID: 4019307
DOI: 10.7164/antibiotics.38.555

Abstract

A new species of a new genus of the Actinomycetales was discovered, Kibdelosporangium aridum. This strain produces a new family of glycopeptide antibiotics designated aridicins, that contain an unusual glycolipid constituent. They inhibit Gram-positive bacteria, including staphylococci, enterococci and Clostridium sp.

MeSH terms

Actinomycetales / classification*
Actinomycetales / cytology
Actinomycetales / physiology
Animals
Anti-Bacterial Agents* / biosynthesis*
Anti-Bacterial Agents* / pharmacology
Bacteria / drug effects
Glycopeptides / biosynthesis
Glycopeptides / pharmacology
Mice

Substances

Anti-Bacterial Agents
Glycopeptides
aridicins