Nocardia arseniciresistens sp. nov., isolated from lead-zinc mine tailing

Int J Syst Evol Microbiol. 2025 Apr;75(4). doi: 10.1099/ijsem.0.006738.

Abstract

A strain with aerial hyphae presented, designated KC 131T, was isolated from lead-zinc mine tailings, Lanping, Yunnan province, Southwest China. The strain was Gram-stain-positive, acid-alcohol-fast, aerobic and non-motile. Based on 16S rRNA gene sequence and phylogeny analysis, strains Nocardia ninae NBRC 108245T (98.4%), Nocardia alba YIM 30243T (98.4%) and Nocardia colli CICC 11023T (98.2%) were the most closely related species of strain KC 131T, and the four strains were in one cluster. The meso-diaminopimelic acid, arabinose and galactose were detected in the whole-cell hydrolysates. The mycolic acids were presented, and the major fatty acids (>5%) were C16:0 (30.0%), C18:1 ω9c (12.5%), C18:0 (7.5%), 10-methyl C18:0 (27.3%) and summed feature 3 (C16:1 ω7c and/or C16:1 ω6c; 12.4%). The menaquinone was MK-8 (H4, ω-cyclo), and the major polar lipids were diphosphatidylglycerol and phosphatidylethanolamine. All these features were consistent with the genus Nocardia. Digital DNA-DNA hybridization values between strain KC 131T and N. ninae NBRC 108245T, N. alba DSM 44684T and N. colli CICC 11023T were 23.8%, 20.9% and 23.5%, respectively. The average nucleotide identity values between strain KC 131T and the three strains were 80.0%, 76.5% and 80.0%, respectively. In addition, some physiological and biochemical characteristics were also different. Thus, strain KC 131T represents a novel species of the genus Nocardia, for which the name Nocardia arseniciresistens sp. nov. is proposed. The type strain is KC 131T (=CGMCC 1.19493T=JCM 35916T).

Keywords: Actinomycetota; Nocardia; new taxa.

MeSH terms

  • Bacterial Typing Techniques
  • Base Composition
  • China
  • DNA, Bacterial / genetics
  • Fatty Acids / analysis
  • Fatty Acids / chemistry
  • Lead
  • Mining*
  • Mycolic Acids / analysis
  • Mycolic Acids / chemistry
  • Nocardia* / classification
  • Nocardia* / genetics
  • Nocardia* / isolation & purification
  • Nucleic Acid Hybridization
  • Phospholipids / analysis
  • Phylogeny*
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA
  • Soil Microbiology*
  • Vitamin K 2 / analogs & derivatives
  • Vitamin K 2 / analysis
  • Vitamin K 2 / chemistry
  • Zinc

Substances

  • RNA, Ribosomal, 16S
  • Fatty Acids
  • DNA, Bacterial
  • Lead
  • Zinc
  • Vitamin K 2
  • Mycolic Acids
  • Phospholipids