Pharmacodynamic biomarkers responsive to mutant huntingtin lowering in a Huntington's disease mouse model

Affiliations

• ¹ CHDI Management, Inc., The Company That Manages the Scientific Activities of CHDI Foundation, Inc., 350 7(th) Ave, Suite 200, New York, NY, 10001, USA. Electronic address: Deanna.Marchionini@CHDIFoundation.org.
• ² Molecular Imaging Center Antwerp (MICA), University of Antwerp, Campus Drie Eiken, Room D.UC.059, Universiteitsplein 1, B-2610 Wilrijk, Belgium.
• ³ Bio-Imaging Lab, University of Antwerp, Campus Drie Eiken, Building UC, Room 111, Universiteitsplein 1, B-2610 Wilrijk, Belgium; μNeuro Centre of Excellence, University of Antwerp, Campus Drie Eiken, Building N, D.N. 110, Universiteitsplein 1, B-2610 Wilrijk, Belgium.
• ⁴ Molecular Imaging Center Antwerp (MICA), University of Antwerp, Campus Drie Eiken, Room D.UC.059, Universiteitsplein 1, B-2610 Wilrijk, Belgium; μNeuro Centre of Excellence, University of Antwerp, Campus Drie Eiken, Building N, D.N. 110, Universiteitsplein 1, B-2610 Wilrijk, Belgium.
• ⁵ Evotec International GmbH, Anna-Sigmund-Str. 5, 82061, Neuried, Germany.
• ⁶ CHDI Management, Inc., The Company That Manages the Scientific Activities of CHDI Foundation, Inc., 350 7(th) Ave, Suite 200, New York, NY, 10001, USA.
• ⁷ Rancho Biosciences, 16955 Via Del Campo, Suite 200, San Diego, CA, 92127, USA.
• ⁸ Molecular Imaging Center Antwerp (MICA), University of Antwerp, Campus Drie Eiken, Room D.UC.059, Universiteitsplein 1, B-2610 Wilrijk, Belgium; Bio-Imaging Lab, University of Antwerp, Campus Drie Eiken, Building UC, Room 111, Universiteitsplein 1, B-2610 Wilrijk, Belgium; μNeuro Centre of Excellence, University of Antwerp, Campus Drie Eiken, Building N, D.N. 110, Universiteitsplein 1, B-2610 Wilrijk, Belgium.