Preparation, quality control and application of 99mTc-gluco-ene-diolate for renal scanning

Nuklearmedizin. 1985 Apr;24(2):93-5.


A one-step freeze-dried Sn-glucose kit was developed to be labelled with technetium-99m. TLC, paper chromatography and gel chromatography column scanning techniques (GCS) were used for the determination of the labelling yield of the complex. High radiochemical purity was obtained (98%). In vivo distribution studies were performed in white rats. Maximum uptake in kidneys (28%) was achieved in 15-90 min. The blood disappearance curve studies of the labelled Sn(II)-gluco-ene-diolate in rabbits have shown two disappearance phases of activity from blood with biological half-times of 10 and 150 min for the fast and slow component respectively.

MeSH terms

  • Animals
  • Gluconates / chemical synthesis*
  • Gluconates / metabolism
  • Kidney / diagnostic imaging*
  • Organotechnetium Compounds*
  • Rabbits
  • Radionuclide Imaging
  • Rats
  • Technetium / chemical synthesis*
  • Technetium / metabolism
  • Time Factors
  • Tissue Distribution


  • Gluconates
  • Organotechnetium Compounds
  • technetium Tc 99m tin gluconate
  • Technetium