Cardiac Juvenile Xanthogranulomatosis in an Infant Presenting With Pericardial Effusion

Mohammad Qasim Mehdi; Pezad Doctor; Shannon Kelley; Nicolas Madsen

doi:10.1016/j.jaccas.2024.103218

Cardiac Juvenile Xanthogranulomatosis in an Infant Presenting With Pericardial Effusion

JACC Case Rep. 2025 Apr 16;30(8):103218. doi: 10.1016/j.jaccas.2024.103218. Epub 2025 Feb 26.

Authors

Mohammad Qasim Mehdi¹, Pezad Doctor², Shannon Kelley³, Nicolas Madsen²

Affiliations

¹ Department of Pediatric Cardiology, University of Texas Southwestern, Medical Center, Dallas, Texas, USA. Electronic address: qasim_mehdi94@hotmail.com.
² Department of Pediatric Cardiology, University of Texas Southwestern, Medical Center, Dallas, Texas, USA.
³ Department of Pathology, University of Texas Southwestern, Medical Center, Dallas, Texas, USA.

Abstract

Understanding the origin of pericardial effusion provides insights on management, risk of recurrence, and outcome. In infants, pericardial effusion can have various causes, including multisystem disease, infection, or cardiac tumors. We describe the case of a previously well 4-month-old infant presenting with a large pericardial effusion secondary to cardiac juvenile xanthogranulomatosis.

Keywords: cardiac mass; cardiac tumors; juvenile xanthogranulomatosis; pericardial effusion; pericardiocentesis; tamponade.

Publication types

Case Reports