Circulating Mast Cell Progenitors Are Depleted by Benralizumab in Severe Asthma

Allergy. 2025 Jun;80(6):1797-1800. doi: 10.1111/all.16553. Epub 2025 Apr 19.

Authors

Michael Fricker^{1

2}, John Harrington^{2

3}, Sarah A Hiles^{2

4}, Peter G Gibson^{1

2

3}

Affiliations

¹ School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.
² Asthma and Breathing Research Program, Hunter Medical Research Institute, Newcastle, New South Wales, Australia.
³ Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, New South Wales, Australia.
⁴ School of Psychological Sciences, University of Newcastle, Newcastle, New South Wales, Australia.

No abstract available

Keywords: asthma; benralizumab; eosinophils; interleukin; mast cells; mepolizumab; progenitors; severe asthma; type 2 inflammation.

Publication types

Letter

Grants and funding

GlaxoSmithKline