Xenotransplantation: A Bibliometric Analysis of Current Trends

Xenotransplantation. 2025 Mar-Apr;32(2):e70046. doi: 10.1111/xen.70046.

Abstract

Xenotransplantation, the transplantation of organs or tissues between species, offers a promising solution to the organ donor shortage. This study examines the research landscape of the field, identifying key trends, influential studies, and leading contributors. A search of the Scopus database on June 24, 2024, focused on solid-organ xenotransplantation publications. Articles were analyzed using Vosviewer, Bibliometrix, and Microsoft Excel. The analysis included 1072 articles with 26 066 citations, reflecting substantial impact in transplantation research. The average citations per document were 24.32, with an annual publication growth rate of 7.63%. Key sources included Xenotransplantation, Transplantation, and Transplantation Proceedings. Cooper was the most influential author, and Harvard Medical School was the leading institution. The United States dominated in publication output and citations. The most cited article, by Hering et al. (2006), had 458 citations. The study highlights the significant growth and increasing attention to xenotransplantation, with ongoing trials emphasizing its potential. This analysis provides insights into the field's progress and serves as a guide for future translational research to advance xenotransplantation toward clinical application.

Keywords: bibliometric; organ transplant; transplant; trends; xenotransplant.

MeSH terms

  • Animals
  • Bibliometrics*
  • Heterografts*
  • Humans
  • Publications
  • Transplantation, Heterologous* / methods
  • Transplantation, Heterologous* / trends