Workshop Report-Heterogeneity and Successful Aging Part II: Approaches to Investigate Heterogeneity in Aging Research

J Gerontol A Biol Sci Med Sci. 2025 Apr 7;80(5):glaf021. doi: 10.1093/gerona/glaf021.

Abstract

Heterogeneity in aging is a fundamental biological process arising from multifactorial etiologies, including genetic, lifestyle, and socioeconomic factors. Modeling this heterogeneity in animal systems is critical for elucidating the underlying mechanisms of aging and for leveraging these insights in translational research. Here we present part II, a summary of the model organism research presented at the NIA Heterogeneity and Successful Aging workshop, held in May 2023.

Keywords: Age-related pathology; Animal model; Anti-aging; Biodemography; Bioinformatics; Biology of aging; Frailty.

MeSH terms

  • Aging* / genetics
  • Aging* / physiology
  • Animals
  • Biomedical Research*
  • Humans
  • Models, Animal