Prevalence of Common Contact Allergens in Topical Diaper Preparations for Infants

Jessica Johnson; Catalina Matiz; Shehla Admani

doi:10.1111/pde.15945

Prevalence of Common Contact Allergens in Topical Diaper Preparations for Infants

Pediatr Dermatol. 2025 Sep-Oct;42(5):1030-1033. doi: 10.1111/pde.15945. Epub 2025 Apr 22.

Authors

Jessica Johnson¹, Catalina Matiz², Shehla Admani³

Affiliations

¹ Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA.
² Kaiser, Department of Dermatology, Southern California Permanente Medical Group, San Diego, California, USA.
³ Department of Dermatology, Stanford University School of Medicine, Palo Alto, California, USA.

PMID: 40263737
DOI: 10.1111/pde.15945

Abstract

In cases of persistent perineal dermatitis (PD), allergic contact dermatitis should be considered and common potential allergens avoided in topical diaper preparations. Our study reviewed the best-selling diaper preparations on a popular website to identify the number and types of allergens in each product, based on the 2018 Pediatric Baseline Patch Test Series and North American Contact Dermatitis Group-70. Of the products reviewed, 21/25 (84%) percent contained one or more potential allergens. Additionally, we provide a list of products that do not have ingredients contained on either potential allergen list.

MeSH terms

Administration, Topical
Allergens* / adverse effects
Allergens* / analysis
Dermatitis, Allergic Contact* / diagnosis
Dermatitis, Allergic Contact* / epidemiology
Dermatitis, Allergic Contact* / etiology
Diaper Rash* / etiology
Diapers, Infant* / adverse effects
Humans
Infant
Patch Tests
Prevalence

Substances

Allergens