The specificity of triacylglycerol synthesis for medium-chain fatty acids in rat and human adipose preparations

Biochim Biophys Acta. 1985 Aug 22;836(1):63-6. doi: 10.1016/0005-2760(85)90220-6.

Abstract

The availability of medium-chain fatty acids as substrates for triacylglycerol synthesis was studied in cultured and suspended rat adipocytes and in pieces of human adipose tissue. Octanoate was virtually excluded from glycerol 3-phosphate esterification while serving as a substrate for diacylglycerol esterification. This specificity was similar to that of cultured rat hepatocytes.

MeSH terms

  • Adipose Tissue / metabolism*
  • Animals
  • Caprylates / metabolism
  • Fatty Acids / metabolism*
  • Glycerophosphates / metabolism
  • Humans
  • In Vitro Techniques
  • Male
  • Mathematics
  • Palmitic Acid
  • Palmitic Acids / metabolism
  • Rats
  • Substrate Specificity
  • Triglycerides / biosynthesis*

Substances

  • Caprylates
  • Fatty Acids
  • Glycerophosphates
  • Palmitic Acids
  • Triglycerides
  • Palmitic Acid
  • alpha-glycerophosphoric acid
  • octanoic acid