The cellular basis for middle-age spread

Science. 2025 Apr 25;388(6745):360. doi: 10.1126/science.adx1198. Epub 2025 Apr 24.

Authors

Yong Geun Jeon¹, Jae Bum Kim¹

Affiliation

¹ National Leader Research Initiatives Center for Adipocyte Structure and Function, Institute of Molecular Biology and Genetics, School of Biological Sciences, Seoul National University, Seoul, South Korea.

PMID: 40273264
DOI: 10.1126/science.adx1198

Abstract

Age-specific adipocyte progenitors drive visceral adipose tissue expansion in middle age.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adipocytes* / cytology
Adipocytes* / physiology
Aging* / physiology
Animals
Humans
Intra-Abdominal Fat* / cytology
Mice
Middle Aged
Obesity / pathology
Stem Cells* / cytology
Stem Cells* / physiology