Polycaprolactone (PCL) is a bioresorbable, biostimulatory polymer offering unique advantages in non-surgical facial rejuvenation, including immediate tissue support and long-term collagen stimulation. This manuscript introduces a novel zone-based framework to guide the use of PCL in achieving facial lifting and contouring. The approach segments the face into 3 zones: zone 1 (red) for lateral lifting, zone 2 (blue) for volumization, and zone 3 (green) for 3-dimensional enhancement, tailored to Asian facial anatomy. By targeting zone 1, the lateral hairline, PCL injections can create a lifting effect by strengthening ligamentous structures and redistributing facial tension. Two split-face case studies demonstrate the efficacy and safety of this approach in addressing midface sagging, nasolabial folds, and jowling, avoiding the facial overfilled syndrome. This innovative technique offers a safe, effective, and anatomically informed method for facial rejuvenation.
Keywords: Anatomic considerations; facial lifting; injection techniques; non-surgical rejuvenation; polycaprolactone (PCL).
Copyright © 2025 by Mutaz B. Habal, MD.