Highlights of 2024: The rising role of age-associated B cells in autoimmune diseases

Adrian Ys Lee; Joanne H Reed

doi:10.1111/imcb.70023

Highlights of 2024: The rising role of age-associated B cells in autoimmune diseases

Immunol Cell Biol. 2025 Jul;103(6):500-503. doi: 10.1111/imcb.70023. Epub 2025 Apr 27.

Authors

Adrian Ys Lee^{1

2}, Joanne H Reed¹

Affiliations

¹ Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, Faculty of Medicine and Health, University of Sydney, Westmead, NSW, Australia.
² Department of Immunology, Westmead Hospital and Institute of Clinical Pathology and Medical Research, NSW Health Pathology, Westmead, NSW, Australia.

PMID: 40288955
DOI: 10.1111/imcb.70023

Abstract

In this Research Highlight, we explore 5 influential basic and translational articles published in 2024 that shed light on the biology of age-associated B cells (ABCs) and their emerging role in autoimmunity.

Keywords: age‐associated B cells; autoantibody; autoimmune disease.

MeSH terms

Aging* / immunology
Animals
Autoimmune Diseases* / immunology
Autoimmunity / immunology
B-Lymphocytes* / immunology
Humans

Abstract

MeSH terms

Grants and funding