The comparative effectiveness of progressive relaxation training on pain characteristics, attack frequency, activity self-efficacy, and pain-related disability in women with episodic tension-type headache and migraine

PLoS One. 2025 Apr 28;20(4):e0320575. doi: 10.1371/journal.pone.0320575. eCollection 2025.

Abstract

Background and purpose: Episodic tension headache (TTH) and migraine, both categorized as primary headache types, account for 60-90% of headache complaints and are three times more common among young women. This study aimed to explore the comparative effectiveness of progressive relaxation training (PRT) on pain characteristics, attack frequency, activity self-efficacy, and pain-related disability in women with episodic TTH and migraine.

Materials and methods: This study was registered at ClinicalTrials.gov (NCT06050382). This prospective study included women with episodic TTH (n=20) and migraine (n=20). The pain intensity, impact of headaches on life, activity self-efficacy, pain catastrophizing, and pain-related disability levels of both groups were measured using the Visual Analog Scale (VAS), Headache Impact Test (HIT-6), Occupational Self-Assessment Scale (OSAS), Pain Catastrophizing Scale (PCS), and World Health Organization Disability Assessment Schedule 2 (WHODAS-II) pre- and post-intervention, respectively. Both TTH and migraine groups received PRT twice a week for six weeks.

Results: Within-group comparisons showed significant decreases in attack frequency, VAS, HIT-6, PCS, and WHODAS-II scores in both groups post-intervention (p<0.001). Also, both groups showed an increase in OSAS proficiency scores (p<0.001). The between-group comparison showed that the attack frequency, VAS, HIT-6, PCS, and WHODAS-II scores were lower in the migraine group than the TTH group. However, all sub-scores of the OSAS were higher in the migraine group (p<0.001).

Conclusions: PRT showed positive effects on pain intensity, attack frequency, activity self-efficacy, and pain-related disability in both groups, more so in the TTH group.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Adult
  • Disability Evaluation
  • Female
  • Humans
  • Migraine Disorders* / physiopathology
  • Migraine Disorders* / psychology
  • Migraine Disorders* / therapy
  • Pain Measurement
  • Persons with Disabilities
  • Prospective Studies
  • Relaxation Therapy* / methods
  • Self Efficacy*
  • Tension-Type Headache* / physiopathology
  • Tension-Type Headache* / psychology
  • Tension-Type Headache* / therapy
  • Treatment Outcome
  • Young Adult

Associated data

  • ClinicalTrials.gov/NCT06050382