In 1923, H.R. Carter published a seminal treatise on the possibility of yellow fever virus spreading to the Asia Pacific region, where large numbers of susceptible people were at risk of infection. This paper marks the 100th anniversary of that publication, and posits that, despite many public health advances, global trends increase the likelihood of yellow fever virus geographic spread. Potential reasons for the failure of the virus to spread are discussed.
© 2025. The Authors. Parts of this work were authored by US Federal Government authors and are not under copyright protection in the US; foreign copyright protection may apply.