An incidental pulmonary amyloidoma detected during 18F-FDG PET/CT assessment of large vessel vasculitis

George Ashton; Karan Bir Singh; Max Yan; Monica A Rossleigh; Anthony M Sammel; Ivan Ho Shon

doi:10.1016/j.radcr.2025.03.079

An incidental pulmonary amyloidoma detected during ¹⁸F-FDG PET/CT assessment of large vessel vasculitis

Radiol Case Rep. 2025 Apr 17;20(7):3347-3351. doi: 10.1016/j.radcr.2025.03.079. eCollection 2025 Jul.

Authors

George Ashton¹, Karan Bir Singh¹, Max Yan², Monica A Rossleigh^{1

3}, Anthony M Sammel^{4

3}, Ivan Ho Shon^{1

3}

Affiliations

¹ Department of Nuclear Medicine and PET, The Prince of Wales and Sydney Children's Hospitals, Barker Street, Randwick, NSW 2031, Australia.
² New South Wales Health Pathology, The Prince of Wales Hospital, Barker Street, Randwick, NSW 2031, Australia.
³ Discipline of Medicine, Randwick Clinical Campus, UNSW Medicine & Health, High Street and Botany Street, Kensington, NSW 2033, Australia.
⁴ Department of Rheumatology, The Prince of Wales Hospital, Barker Street, Randwick, NSW 2031, Australia.

Abstract

A 78-year-old woman underwent an ¹⁸F-FDG PET/CT scan as part of the investigation for giant cell arteritis. This demonstrated active large vessel vasculitis along with a moderately metabolically active pulmonary nodule in the left upper lobe; the appearances of which were concerning for malignancy. Subsequent biopsy of the pulmonary nodule was consistent with an amyloidoma. The nodule remained metabolically stable and of a similar appearance on repeat imaging performed 3 years later.

Keywords: Amyloidoma; FDG PET/CT; Pulmonary nodule; Vasculitis.

Publication types

Case Reports