The Last Decade in Tricuspid Regurgitation: How Imaging Shaped a Field

JACC Cardiovasc Imaging. 2025 Sep;18(9):1013-1041. doi: 10.1016/j.jcmg.2025.03.003. Epub 2025 Mar 29.

Abstract

The tricuspid valve has become a major focus of novel structural heart interventions, with the Conformité Européenne approval of 5 devices in Europe and the U.S. Food and Drug Administration approval of 2 devices in the United States. Multiple meta-analyses and large population-based registries have shown that although significant tricuspid regurgitation (TR) often accompanies left heart or pulmonary vascular diseases, it is associated with an increased risk of mortality and a reduced quality of life after adjusting for these comorbidities. Echocardiography remains the imaging modality of choice for diagnosing the etiology and assessing the severity of TR. However, advanced imaging techniques have played an essential role in the rapid advancement of the structural field and, in particular, transcatheter interventions for TR. Herein, we review the advances made in this field, focusing on the role that imaging has played in shaping a new field of study.

Keywords: echocardiography; multimodality imaging; tricuspid regurgitation.

Publication types

  • Review

MeSH terms

  • Cardiac Catheterization / adverse effects
  • Cardiac Catheterization / instrumentation
  • Heart Valve Prosthesis Implantation* / adverse effects
  • Heart Valve Prosthesis Implantation* / instrumentation
  • Hemodynamics
  • Humans
  • Predictive Value of Tests
  • Prognosis
  • Severity of Illness Index
  • Tricuspid Valve Insufficiency* / diagnosis
  • Tricuspid Valve Insufficiency* / diagnostic imaging
  • Tricuspid Valve Insufficiency* / mortality
  • Tricuspid Valve Insufficiency* / physiopathology
  • Tricuspid Valve Insufficiency* / therapy
  • Tricuspid Valve* / diagnostic imaging
  • Tricuspid Valve* / physiopathology
  • Tricuspid Valve* / surgery