Partial resolution of ranitidine-associated delirium with physostigmine: case report

J Clin Psychiatry. 1985 Sep;46(9):400-1.


A healthy 25-year-old woman experienced probable ranitidine-induced confusion that partially resolved with intravenous physostigmine. The only known prior report of confusion associated with this relatively new agent was in a severely ill 86-year-old woman. Clinicians should be alert for mental status changes with ranitidine and consider a trial of physostigmine when indicated.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Delirium / chemically induced*
  • Delirium / drug therapy
  • Female
  • Humans
  • Infusions, Parenteral
  • Physostigmine / administration & dosage
  • Physostigmine / therapeutic use*
  • Ranitidine / adverse effects*


  • Ranitidine
  • Physostigmine