Release of microplastics during dental procedures and denture wear: Impact on dental personnel and patients

Abstract

Plastic products are widely used in modern dentistry, including dental instruments and resin-based materials. In recent years, microplastics (MPs) that are generated from plastic products have been demonstrated to pose negative impacts on human health. However, the possible exposure of MP during dental procedures has been rarely explored. This study aims to assess the MP exposure faced by both dental personnel and patients via simulating the wear and cleaning procedures of dentures, as well as the grinding of resin-based materials under clinical settings. Additionally, environmental samples of the dental clinic were collected to determine the types and concentrations of MP settlement. The biological toxicity of the particles has also been evaluated. Results showed that denture releases MP particles into artificial saliva during soaking and cleaning processes. During the grinding of resin-based materials, MP could be detected in settlements with decreased concentration as the increase of distance from 25 cm to 100 cm. A substantial accumulation of particles was observed in the clinic within a single day. Grinding-generated MPs exhibited biological toxicity toward oral keratinocyte cells and triggered inflammation in macrophages at concentrations that could be encountered in clinical exposure. This study confirms the presence of MP exposure during dental procedures, providing valuable insights for the development of improved management regulations and pollution control measures in dental practice.

Keywords: Biocompatibility; Dentistry; Laser direct infrared (LDIR); Microplastic; Resin-based materials.