The Use of Pharmacogenomics in Cardiovascular Care

Claire Spahn; Trina Walker; Seda Byurat; Latha Palaniappan

doi:10.1016/j.cnur.2024.12.007

The Use of Pharmacogenomics in Cardiovascular Care

Nurs Clin North Am. 2025 Jun;60(2):305-320. doi: 10.1016/j.cnur.2024.12.007. Epub 2025 Feb 20.

Authors

Claire Spahn¹, Trina Walker², Seda Byurat³, Latha Palaniappan⁴

Affiliations

¹ Department of Pharmacy, Stanford Health Care, 500 Pasteur Drive, Palo Alto, CA 94304, USA. Electronic address: cspahn@stanfordhealthcare.org.
² College of Nursing, Creighton University.
³ Kaiser Permanente Northern California, Stanford University, Stanford, CA, USA.
⁴ General Medical Disciplines, Stanford University School of Medicine, Stanford, CA, USA.

PMID: 40345762
DOI: 10.1016/j.cnur.2024.12.007

Abstract

Pharmacogenomics (PGx)-the study of how one's genes affect their response to drugs-has implications for every medical subspecialty, including cardiology. This article discusses evidence-based resources that provide guidance for interpreting and applying PGx results in patient care. All health care providers, including frontline nurses, should understand this important tool for patient care.

Keywords: Beta blocker; Cardiovascular; Clopidogrel; Pharmacogenomics; Statin; Warfarin.

Publication types

Review

MeSH terms

Cardiovascular Diseases* / drug therapy
Cardiovascular Diseases* / genetics
Humans
Pharmacogenetics*