Involvement of IL-13-Induced Dysregulation of BDNF-NTRK2 Pathway in Symptoms of Eosinophilic Esophagitis

Kasumi Osonoi; Akinari Sawada; Yuki Maekawa; Mari Yamaguchi; Shingo Yamada; Kazuhiro Matsuyama; Mark Rochman; Marc E Rothenberg; Xiaobo Han; Naoki Matsuda; Ikuro Suzuki; Fumio Tanaka; Yasuhiro Fujiwara; Tetsuo Shoda

doi:10.1111/all.16592

Involvement of IL-13-Induced Dysregulation of BDNF-NTRK2 Pathway in Symptoms of Eosinophilic Esophagitis

Allergy. 2025 Oct;80(10):2894-2897. doi: 10.1111/all.16592. Epub 2025 May 13.

Authors

Kasumi Osonoi¹, Akinari Sawada², Yuki Maekawa¹, Mari Yamaguchi¹, Shingo Yamada¹, Kazuhiro Matsuyama^{1

3}, Mark Rochman¹, Marc E Rothenberg^{1

4}, Xiaobo Han⁵, Naoki Matsuda⁵, Ikuro Suzuki⁵, Fumio Tanaka², Yasuhiro Fujiwara², Tetsuo Shoda^{1

4}

Affiliations

¹ Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
² Department of Gastroenterology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
³ Department of Computer Science, University of Cincinnati, Cincinnati, Ohio, USA.
⁴ Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
⁵ Department of Electronics, Graduate School of Engineering, Tohoku Institute of Technology, Sendai, Miyagi, Japan.

No abstract available

Keywords: EoE diagnostic panel; IL‐13; asymptomatic esophageal eosinophilia; brain‐derived neurotrophic factor; eosinophilic esophagitis; iPSC‐derived sensory neurons; neuropathic and inflammatory pain panel; neurotrophic receptor tyrosine kinase 2.

Publication types

Letter

Publication types

Grants and funding