Serum prolactin and cortisol levels in evaluation of pseudoepileptic seizures

Ann Neurol. 1985 Jul;18(1):87-9. doi: 10.1002/ana.410180115.


In 6 patients with epilepsy, a twofold increase in serum prolactin levels followed true epileptic seizures, but no significant change followed pseudoepileptic attacks in 6 other patients. Serum prolactin concentration is a useful biochemical marker to distinguish between epileptic and pseudoepileptic seizures. Serum cortisol levels also increased after epileptic seizures, but diurnal and individual variations render the cortisol level a less reliable indicator of such attacks.

Publication types

  • Comparative Study

MeSH terms

  • Diagnosis, Differential
  • Epilepsy / blood*
  • Epilepsy / diagnosis
  • Humans
  • Hydrocortisone / blood*
  • Prolactin / blood*


  • Prolactin
  • Hydrocortisone