Impact of smartphone activated first responders on provision of bystander CPR, bystander AED and outcomes for out-of-hospital cardiac arrest (OHCA)

Resuscitation. 2025 Jul:212:110645. doi: 10.1016/j.resuscitation.2025.110645. Epub 2025 May 16.

Abstract

Background: The smartphone application to activate a community first responder (myResponder) was launched in 2015 to activate volunteer first responders for Out-of-Hospital Cardiac Arrest (OHCA) patients in Singapore. This study aimed to investigate the impact of myResponder on provision of bystander CPR, bystander AED, and patient survival outcomes.

Methods: This was a retrospective analysis using the Singapore Pan-Asian Resuscitation Outcomes Study between 2016 and 2019 that included adult non-traumatic OHCA patients. Patients were categorized into myResponder activated and non-activated groups. The primary outcomes were bystander CPR and bystander AED. The secondary outcome was survival at 30-days with favourable neurological outcomes (cerebral performance category 1-2). A multivariable logistic regression analysis was performed and we reported adjusted odds ratio [aOR] and 95% confidence interval for the effect of activation.

Results: 9,167 patients were included in this analysis. The median (Interquartile range, IQR) age was 71 (59-82) years. The activated group comprised 5,499 (60%) of cases. The activated group was associated with higher bystander CPR (aOR [95%CI]: 5.69 [4.89-6.62]) and bystander AED (aOR [95% CI]: 2.23 [1.82-2.74]) compared to non-activated group. The activated group was associated with better survival at 30 days with favourable neurological outcomes (aOR [95% CI]: 1.54 [1.11-2.15]).

Conclusion: We found that the implementation of technology-activated first responders was associated with an improvement in the performance of bystander CPR, bystander AED application, and OHCA outcomes in an urban area. Further efforts should be made to promote the use of activated first responders in EMS systems.

Keywords: Bystander CPR; Cardio-pulmonary resuscitation; Out-of-hospital cardiac arrest; Smartphone application; myResponder.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cardiopulmonary Resuscitation* / instrumentation
  • Cardiopulmonary Resuscitation* / methods
  • Cardiopulmonary Resuscitation* / statistics & numerical data
  • Defibrillators* / statistics & numerical data
  • Emergency Medical Services* / methods
  • Emergency Responders* / statistics & numerical data
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mobile Applications*
  • Out-of-Hospital Cardiac Arrest* / mortality
  • Out-of-Hospital Cardiac Arrest* / therapy
  • Retrospective Studies
  • Singapore / epidemiology
  • Smartphone*