Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985 Jan;18(1):59-66.
doi: 10.1002/dev.420180105.

Effects of a Commercial Soy Lecithin Preparation on Development of Sensorimotor Behavior and Brain Biochemistry in the Rat

Effects of a Commercial Soy Lecithin Preparation on Development of Sensorimotor Behavior and Brain Biochemistry in the Rat

J M Bell et al. Dev Psychobiol. .

Abstract

Pregnant rat dams and offspring were exposed to a 5 or 2% soy lecithin preparation or a control diet. Enrichment was either lifelong beginning at gestation, limited to the time preceding, or the time following weaning, or absent (constituting a "pure" control group). The most marked early sensorimotor deficits (reflex righting and swimming development) were seen in the 5% soy lecithin preparation group, although all soy lecithin preparation-exposed offspring had elevated brain/body weight ratios and choline acetyltransferase levels. Later, animals exposed to lifelong 5 or 2% soy lecithin preparations were hypoactive, had poor postural reflexes, and showed attenuated morphine analgesia. The results indicate that dietary soy lecithin preparation enrichment during development leads to behavioral and neurochemical abnormalities in the exposed offspring.

Similar articles

See all similar articles

Cited by 1 article

Publication types

LinkOut - more resources

Feedback