Early versus conventional loading for fully guided immediate implant placement in molar sites: a randomized controlled clinical study

Int J Implant Dent. 2025 May 20;11(1):39. doi: 10.1186/s40729-025-00624-8.

Abstract

Purpose: To evaluate early versus conventional loading in immediate implants for molars. This study aims to answer the following PICO (Patient, Intervention, Comparison, and Outcome) question: In patients over 18 years of age, does early loading of immediately placed implants in molar areas result in a similar implant survival rate and marginal bone loss as conventional loading?

Methods: Twenty-seven patients (15 women and 12 men) received a total of 30 implants immediately after molar extraction. The surgical treatment protocol entailed atraumatic tooth extraction without flap elevation. Non-invasive quantitative analyses were used to assess implant stability. After an uneventful healing period, the 30 implants were restored with screw-retained monolithic zirconia prosthesis, half of which after 6 weeks (G1) and the other half after 3 months (G2).

Results: Regarding the survival rate, the Kaplan-Meier and log-rank test showed that there was no statistically significant difference between both groups (p = 1). Implant stability quotient at the prosthetic phase of both groups (6 weeks in G1 and 3 months in G2) revealed no statistically significant difference (G1 RFA74.4 (SD 5.54) - DCA 79.07 (SD 5.75))/G2 RFA 73.67 (SD 5.7), - DCA78.93 (SD 4.48).

Conclusions: Early loading of immediately placed implants in molar sites is considered a predictable treatment modality provided that ideal implant position and adequate insertion torque are achieved.

Keywords: Damping capacity analysis; Early loading; Fully guided; Immediate implants; Molar area; Resonance frequency analysis.

Publication types

  • Randomized Controlled Trial
  • Comparative Study

MeSH terms

  • Adult
  • Dental Implantation, Endosseous* / methods
  • Dental Implants
  • Dental Prosthesis, Implant-Supported
  • Female
  • Humans
  • Immediate Dental Implant Loading* / methods
  • Male
  • Middle Aged
  • Molar* / surgery
  • Tooth Extraction
  • Treatment Outcome

Substances

  • Dental Implants