Initial development and validation of a disease-specific resilience measure for inflammatory bowel disease: the RISE-IBD instrument

Michelle Mendiolaza; Camila Vicioso; Wamia Siddiqui; Karan Lingineni; Ksenia Gorbenko; Parul Agarwal; Laurie Keefer

doi:10.1186/s12876-025-03971-3

Initial development and validation of a disease-specific resilience measure for inflammatory bowel disease: the RISE-IBD instrument

BMC Gastroenterol. 2025 May 21;25(1):390. doi: 10.1186/s12876-025-03971-3.

Authors

Michelle Mendiolaza¹, Camila Vicioso², Wamia Siddiqui², Karan Lingineni³, Ksenia Gorbenko^{4

5}, Parul Agarwal⁵, Laurie Keefer⁶

Affiliations

¹ Institute for Translational Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY, 10029, USA. michelle.mendiolaza@icahn.mssm.edu.
² Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
³ Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
⁴ Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
⁵ Institute for Healthcare Delivery Science, Mount Sinai Health System, New York, NY, USA.
⁶ Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Abstract

Background: Inflammatory bowel diseases (IBDs) have a substantial effect on the well-being and quality of life of patients. While resilience may help alleviate psychological and physical burdens in individuals with IBD, there is no disease-specific measure that currently exists to accurately quantify this construct in the context of IBD. This study aimed to psychometrically validate the new Resilience Scale for IBD (RISE-IBD).

Methods: A preliminary scale was developed including 17 items generated from a qualitative study that centered on patient focus group discussions, conversations with IBD healthcare providers, and evaluation of two validated resilience measures. In this cross-sectional study, the scale's reliability, validity, and consistency were assessed in a sample of 91 patients with IBD.

Results: The 17-item RISE-IBD was reduced to a 14-item measure. The revised RISE-IBD, comprising four resilience domains (Disease Acceptance, Self-Reliance, Flexibility, Persistence), demonstrated strong internal consistency (Cronbach's α = 0.82) and excellent re-test reliability (r = 0.91). The scale exhibited significantly positive correlations with the Connor-Davidson Resilience Scale (r = 0.74) and Brief Resilience Scale (r = 0.59), as well as with a disease-specific quality of life scale, the IBD Questionnaire (τ = 0.33). It also showed significantly negative associations with psychological distress measured by the Brief Symptom Inventory (τ = -0.36) and IBD-related disability assessed by the IBD Disability Index (τ = -0.30).

Conclusions: The RISE-IBD demonstrates its strong potential as a psychometrically reliable tool for assessing resilience in patients with IBD. By evaluating resilience across multiple domains, healthcare providers can gain a thorough understanding of patients' coping mechanisms and tailor interventions accordingly. Future research should focus on further strengthening the scale's psychometric properties by validating its use across diverse gastrointestinal patient populations and exploring the relationship between resilience and key IBD outcomes.

Keywords: Disease management; Inflammatory bowel disease; Psychometric validation; Resilience; Scale development.

Publication types

Validation Study

MeSH terms

Adult
Aged
Cross-Sectional Studies
Female
Humans
Inflammatory Bowel Diseases* / psychology
Male
Middle Aged
Psychometrics
Quality of Life
Reproducibility of Results
Resilience, Psychological*
Surveys and Questionnaires
Young Adult