VEXAS syndrome caused by a UBA1 mutation is complicated by recurrent infections leading to hemophagocytic lymphohistiocytosis

Genes Dis. 2025 Jan 22;12(5):101540. doi: 10.1016/j.gendis.2025.101540. eCollection 2025 Sep.

Yu Tang^{1

2}, Hongfei Cui^{1

2}, Hongjun Zhao^{2

3

4

5}, Hui Luo^{2

3

4

5}, Xiaoxia Zuo^{2

3

4

5}, Junjiao Wu^{2

3

4

5}

¹ Aging Research Center, Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
² National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
³ Department of Rheumatology and Immunology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
⁴ Provincial Clinical Research Center for Rheumatic and Immunologic Diseases, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
⁵ Hunan Provincial Skin Immunization and Medical Center, Changsha, Hunan 410008, China.

No abstract available

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