A Golgi and morphometric study of the ectopic granule cells in the molecular layer of the rat cerebellum

Brain Res. 1985 Oct 21;345(2):398-401. doi: 10.1016/0006-8993(85)91025-x.


The morphological types of isolated ectopic granule cells (EGCs) were examined with Golgi-Rio Hortega staining in the cerebellar molecular layer of adult normal rats. The EGCs showed a significant reduction in the number of dendrites (mean 2.42 +/- 0.07) with respect to the controls (mean 3.97 +/- 0.09), and they usually exhibited poorly developed dendritic terminals. The karyometric analysis on semithin sections indicated that the average nuclear area in EGCs was significantly smaller (16.62 +/- 0.20 micron 2) than in normally positioned granule cells (21.08 +/- 0.24 micron 2).

MeSH terms

  • Animals
  • Cell Movement
  • Cell Nucleus / ultrastructure
  • Cerebellar Cortex / cytology*
  • Female
  • Male
  • Rats
  • Rats, Inbred Strains