An unusual variant chromosome 9 with an extra C-negative, G-dark segment in the short arm

Clin Genet. 1985 Aug;28(2):162-5. doi: 10.1111/j.1399-0004.1985.tb00377.x.


An unusual variant chromosome 9 is described in a mother and a daughter: an extra G-dark, C-negative and G-11 negative chromosomal segment is present in the short arm in the absence of apparent phenotypic effects. This extra material is also Ag-As negative and exhibits a fluorescence similar in intensity to that of band 9q21 when stained by QFQ and DAPI/AMD, and to that of band 9p13 in RBA-banded preparations; it is slightly less fluorescent when R-banded by chromomycin A3. The possibility of an association with an increased risk of spontaneous abortion is presented.

Publication types

  • Case Reports

MeSH terms

  • Chromosome Aberrations / genetics*
  • Chromosome Banding
  • Chromosome Disorders
  • Chromosomes, Human, 6-12 and X*
  • Female
  • Humans
  • Infant, Newborn
  • Pedigree
  • Tongue / abnormalities*